Ozempic and Wegovy Don’t Have to Be Lifetime Medications: Using Semaglutide and Tirzepatide to Transform Your Diet
Bruce Gutman Bruce Gutman

Ozempic and Wegovy Don’t Have to Be Lifetime Medications: Using Semaglutide and Tirzepatide to Transform Your Diet

The growing popularity of medications like Ozempic (semaglutide) and Wegovy (another version of semaglutide) for weight loss has brought attention to their ability to help individuals shed pounds and maintain healthier lifestyles. Recently, another medication, tirzepatide (marketed as Mounjaro for type 2 diabetes), has also shown promise for weight management. However, what is less frequently discussed is how these medications can be seen as tools rather than lifelong solutions.

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Groundbreaking Study on Ketamine-Assisted Therapy for Alcohol Use Disorder
Bruce Gutman Bruce Gutman

Groundbreaking Study on Ketamine-Assisted Therapy for Alcohol Use Disorder

Alcohol use disorder (AUD) is a significant public health issue, affecting millions of adults worldwide, including in the United States. Despite the widespread nature of this problem, only about 20% of those with alcohol issues receive treatment, and the success rate for long-term sobriety remains low. Approximately 75% of individuals who quit drinking relapse within a year. The consequences of AUD extend beyond the individual, impacting families, communities, and society at large. The financial burden on healthcare systems is substantial, with costs estimated in the billions. In response to this pressing issue, researchers in the United Kingdom are conducting the MORE-KARE study to explore the potential of ketamine-assisted psychological therapy to improve treatment outcomes for individuals with severe alcohol use disorder.

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The Transformative Power of Ketamine: Three Personal Stories of Success
Bruce Gutman Bruce Gutman

The Transformative Power of Ketamine: Three Personal Stories of Success

Ketamine, a dissociative anesthetic developed in the 1960s, has gained renewed interest in recent years for its potential in treating mental health conditions such as depression, anxiety, and PTSD. Unlike traditional antidepressants, which can take weeks to show effects, ketamine often provides rapid relief. Here are three stories of individuals who have found success with ketamine treatment.

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 Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression
Bruce Gutman Bruce Gutman

Ketamine vs Electroconvulsive Therapy for Treatment-Resistant Depression

Depression is a significant global health issue, and for those with treatment-resistant depression (TRD), finding an effective treatment can be a daunting challenge. A recent study published in JAMA Network Open sheds light on the benefits of two major treatments for TRD: Ketamine and Electroconvulsive Therapy (ECT). This study provides critical insights that can help patients and healthcare providers make more informed decisions.

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Ketamine Treatment for Depression: Safe for Long-Term Use
Bruce Gutman Bruce Gutman

Ketamine Treatment for Depression: Safe for Long-Term Use

Ketamine, a medication traditionally used as an anesthetic, has gained attention for its rapid-acting antidepressant effects, particularly for those struggling with treatment-resistant depression (TRD). Unlike typical antidepressants that can take weeks to show benefits, ketamine often works within hours. However, the effects of a single dose are usually short-lived, leading doctors to develop multidose treatment plans to extend the benefits.

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Breaking Your Sugar Addiction with Modern Weight Loss Medications
Bruce Gutman Bruce Gutman

Breaking Your Sugar Addiction with Modern Weight Loss Medications

Sugar, particularly in its refined form, is one of the most harmful ingredients in our diet today. High consumption of sugar is linked to a slew of health issues, including obesity, type 2 diabetes, heart disease, and dental decay. It induces rapid spikes in blood glucose and insulin levels, playing a crucial role in metabolic syndrome—a cluster of conditions that heightens the risk of heart disease and other health problems. Additionally, sugar contributes to inflammation and is linked to the aging process and the onset of certain cancers.

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Insights from the Phase 2 Trial of Extended-Release Ketamine Tablets
Bruce Gutman Bruce Gutman

Insights from the Phase 2 Trial of Extended-Release Ketamine Tablets

In a groundbreaking study published in Nature, a recent phase 2 clinical trial has brought new hope for patients suffering from treatment-resistant depression (TRD). The trial tested the efficacy and safety of extended-release ketamine tablets (R-107) and presented promising results that could significantly alter the landscape of depression treatment.

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Ketamine Compared to Traditional Antidepressants
Bruce Gutman Bruce Gutman

Ketamine Compared to Traditional Antidepressants

Depression, a multifaceted mental health disorder, affects millions worldwide. While traditional antidepressants like SSRIs, SNRIs, and Tricyclic/Tetracyclic Antidepressants have been the standard treatment for years, ketamine offers a novel approach that goes beyond symptom management, targeting the root causes of depression.

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Understanding Ketamine's Unique Effects on Synaptic Plasticity and Depression Treatment
Bruce Gutman Bruce Gutman

Understanding Ketamine's Unique Effects on Synaptic Plasticity and Depression Treatment

Ketamine, often known as a rapid-acting antidepressant, has generated significant interest in the field of mental health. This article delves into the recent findings from a study titled "Ketamine induced synaptic plasticity operates independently of long-term potentiation" by Michelle K. Piazza, Ege T. Kavalali, and Lisa M. Monteggia. We'll explore the study's key points in a simplified manner to help you grasp how ketamine affects brain function and its implications for treating depression.

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Ketamine vs. Benzodiazepines and SSRIs for Anxiety 
Bruce Gutman Bruce Gutman

Ketamine vs. Benzodiazepines and SSRIs for Anxiety 

Anxiety disorders are among the most common mental health issues worldwide, affecting millions of individuals and significantly impairing their quality of life. Traditionally, benzodiazepines (benzos) and selective serotonin reuptake inhibitors (SSRIs) have been the primary treatments. However, these medications often come with significant drawbacks, including dependency, withdrawal symptoms, and delayed onset of action.

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Misaligned Incentives in Healthcare
Bruce Gutman Bruce Gutman

Misaligned Incentives in Healthcare

At Well3, we believe in providing access to healthcare tools before it's too late. Individuals should be able to access weight loss medications before becoming overweight, and mental health treatments before enduring years of depression and anxiety. We advocate for proactive healthcare, ensuring you receive the necessary tools to address health issues early, before they escalate.

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Deep Work: Our First Ketamine-Assisted Therapy Program
Bruce Gutman Bruce Gutman

Deep Work: Our First Ketamine-Assisted Therapy Program

We are excited to launch our inaugural ketamine-assisted initiative: DEEP Work. This six-week intensive program is tailored for men committed to deep personal healing, growth, and finding a sense of community. Led by Ted Rider, with over three decades of experience in transformative practices, this program blends teaching, spiritual guidance, and coaching to ensure a secure and conducive environment for significant personal development.

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Healing Chronic Stress Damage to the Brain
Bruce Gutman Bruce Gutman

Healing Chronic Stress Damage to the Brain

Chronic stress is a pervasive issue in today's fast-paced world, affecting millions of people and leading to a myriad of health problems. One of the less visible but profoundly impactful consequences of long-term stress is damage to dendrites, the critical components of neurons responsible for transmitting electrical signals in the brain. This article explores how ketamine, a medication once known primarily for its use in anesthesia, is emerging as a potential tool in repairing dendritic damage caused by chronic stress, offering new hope for recovery and mental health restoration.

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What Motivates Me?
Bruce Gutman Bruce Gutman

What Motivates Me?

In seeking healing, I ventured into the realms of ketamine therapy and psychedelic experiences, with a life-altering ayahuasca retreat in Peru addressing deep-seated trauma from my birth. These journeys taught me to energetically release trauma, offer forgiveness, and, when possible, make personal amends.

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Navigating Hormonal Changes in Aging Women
Bruce Gutman Bruce Gutman

Navigating Hormonal Changes in Aging Women

As women age, they often experience symptoms of hormonal imbalances, particularly related to declining estrogen and progesterone levels, commonly associated with menopause. This natural shift can lead to physical changes such as decreased bone density, potentially resulting in osteoporosis, and alterations in body composition with increased fat deposition.

Well3 provides tools to make it easier to make changes in your life.

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Navigating Low Testosterone for Aging Men
Bruce Gutman Bruce Gutman

Navigating Low Testosterone for Aging Men

As men age, experiencing symptoms of low testosterone, often referred to as "Low T," becomes a typical aspect of the aging process. This natural decline can lead to physical changes such as decreased muscle mass and strength, increased body fat, and reduced bone density, potentially resulting in osteoporosis.

Well3 provides tools to make it easier to make changes in your life.

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